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NMNAT3 (aa149-162) Antibody (internal region)

Peptide-affinity purified goat antibody

  • WB - NMNAT3 (aa149-162) Antibody (internal region) AF3589a
    AF3589a (0.1 µg/ml) staining of Human Kidney lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q96T66
Other Accession NP_835471.1, NP_001186976.1, 349565
Reactivity Human
Predicted Dog
Host Goat
Clonality Polyclonal
Concentration 0.5 mg/ml
Isotype IgG
Calculated MW 28322 Da
Additional Information
Gene ID 349565
Other Names Nicotinamide mononucleotide adenylyltransferase 3, NMN adenylyltransferase 3, Nicotinate-nucleotide adenylyltransferase 3, NaMN adenylyltransferase 3,, Pyridine nucleotide adenylyltransferase 3, PNAT-3,, NMNAT3
Format 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsNMNAT3 (aa149-162) Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Function Catalyzes the formation of NAD(+) from nicotinamide mononucleotide (NMN) and ATP. Can also use the deamidated form; nicotinic acid mononucleotide (NaMN) as substrate with the same efficiency. Can use triazofurin monophosphate (TrMP) as substrate. Can also use GTP and ITP as nucleotide donors. Also catalyzes the reverse reaction, i.e. the pyrophosphorolytic cleavage of NAD(+). For the pyrophosphorolytic activity, can use NAD(+), NADH, NaAD, nicotinic acid adenine dinucleotide phosphate (NHD), nicotinamide guanine dinucleotide (NGD) as substrates. Fails to cleave phosphorylated dinucleotides NADP(+), NADPH and NaADP(+). Protects against axonal degeneration following injury.
Cellular Location Mitochondrion
Tissue Location Expressed in lung and spleen with lower levels in placenta and kidney.
Research Areas
Citations (0)

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This antibody is expected to recognize both reported isoforms (NP_835471.1; NP_001186976.1).


Initial-rate kinetics of human NMN-adenylyltransferases: substrate and metal ion specificity, inhibition by products and multisubstrate
analogues, and isozyme contributions to NAD+ biosynthesis. Sorci L, Cimadamore F, Scotti S, Petrelli R, Cappellacci L, Franchetti P,
Orsomando G, Magni G. Biochemistry. 2007 Apr 24;46(16):4912-22. PMID: 17402747

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$ 325.00
Cat# AF3589a
(40 western blots)
Availability: 7-10 days
Bulk Size
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