|Application ||WB, IHC, E|
|Other Accession||NP_000538.3, NP_783650.1, NP_783652.1, NP_783653.1, 7173|
|Calculated MW||102963 Da|
|Other Names||Thyroid peroxidase, TPO, 220.127.116.11, TPO|
|Format||0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||thyroid peroxidase Antibody (C-Term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Iodination and coupling of the hormonogenic tyrosines in thyroglobulin to yield the thyroid hormones T(3) and T(4).|
|Cellular Location||Membrane; Single-pass type I membrane protein|
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Provided below are standard protocols that you may find useful for product applications.
This antibody is expected to recognize all reported isoforms (NP_000538.3; NP_783650.1; NP_783652.1; NP_783653.1).
Antibodies to thyroid peroxidase arise spontaneously with age in NOD.H-2h4 mice and appear after thyroglobulin antibodies. Chen CR, Hamidi S, Braley-Mullen H, Nagayama Y, Bresee C, Aliesky HA, Rapoport B, McLachlan SM. Endocrinology. 2010 Sep;151(9):4583-93. PMID: 20573721
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