ABCC9 / SUR2 Antibody (internal region)
Peptide-affinity purified goat antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| E |
---|---|
Primary Accession | O60706 |
Other Accession | NP_005682.2, NP_064693.2, 10060 |
Predicted | Human, Dog, Cow |
Host | Goat |
Clonality | Polyclonal |
Concentration | 0.5 mg/ml |
Isotype | IgG |
Calculated MW | 174223 Da |
Gene ID | 10060 |
---|---|
Other Names | ATP-binding cassette sub-family C member 9, Sulfonylurea receptor 2, ABCC9, SUR2 |
Format | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | ABCC9 / SUR2 Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | ABCC9 |
---|---|
Synonyms | SUR2 {ECO:0000303|PubMed:31575858} |
Function | Subunit of ATP-sensitive potassium channels (KATP). Can form cardiac and smooth muscle-type KATP channels with KCNJ11. KCNJ11 forms the channel pore while ABCC9 is required for activation and regulation. |
Cellular Location | Membrane {ECO:0000255|PROSITE-ProRule:PRU00441}; Multi-pass membrane protein {ECO:0000255|PROSITE-ProRule:PRU00441} |
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Provided below are standard protocols that you may find useful for product applications.
Background
This antibody is expected to recognize isoforms SUR2A (NP_005682.2) and SUR2B (NP_064693.2).
References
Human oocytes express ATP-sensitive K(+) channels. Du Q, Jovanovi? S, Sukhodub A, Barratt E, Drew E, Whalley KM, Kay V, McLaughlin M, Telfer EE, Barratt CL, Jovanovi? A. Hum Reprod. 2010 Nov;25(11):2774-82. PMID: 20847183
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