|Application ||WB, E|
|Other Accession||NP_001035.1, 6531|
|Calculated MW||68495 Da|
|Other Names||Sodium-dependent dopamine transporter, DA transporter, DAT, Solute carrier family 6 member 3, SLC6A3, DAT1|
|Format||0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||SLC6A3 / DAT Antibody (internal region, near N-Term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Amine transporter. Terminates the action of dopamine by its high affinity sodium-dependent reuptake into presynaptic terminals.|
|Cellular Location||Cell membrane; Multi- pass membrane protein|
|Tissue Location||Highly expressed in substantia nigra.|
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Relationship of DAT1 and adult ADHD to task-positive and task-negative working memory networks. Brown AB, Biederman J, Valera E, Makris N, Doyle A, Whitfield-Gabrieli S, Mick E, Spencer T, Faraone S, Seidman L. Psychiatry Res. 2011 Jul 30;193(1):7-16. Epub 2011 May 18. PMID: 21596533
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