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Progranulin aa248-259 / Granulin-3 Antibody (internal)

Peptide-affinity purified goat antibody

  • WB - Progranulin aa248-259 / Granulin-3 Antibody (internal) AF3703a
    AF3703a (1 µg/ml) staining of A431 lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P28799
Other Accession NP_002078.1, 2896
Reactivity Human
Host Goat
Clonality Polyclonal
Concentration 0.5 mg/ml
Isotype IgG
Calculated MW 63544 Da
Additional Information
Gene ID 2896
Other Names Granulins, Proepithelin, PEPI, Acrogranin, Glycoprotein of 88 Kda, GP88, Glycoprotein 88, Progranulin, Paragranulin, Granulin-1, Granulin G, Granulin-2, Granulin F, Granulin-3, Granulin B, Granulin-4, Granulin A, Granulin-5, Granulin C, Granulin-6, Granulin D, Granulin-7, Granulin E, GRN
Format 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsProgranulin aa248-259 / Granulin-3 Antibody (internal) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name GRN
Function Granulins have possible cytokine-like activity. They may play a role in inflammation, wound repair, and tissue remodeling.
Cellular Location Secreted.
Tissue Location In myelogenous leukemic cell lines of promonocytic, promyelocytic, and proerythroid lineage, in fibroblasts, and very strongly in epithelial cell lines. Present in inflammatory cells and bone marrow. Highest levels in kidney
Research Areas
Citations (0)

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This antibody is expected to recognize the C-Terminal part of Granulin-3.


Rescue of progranulin deficiency associated with frontotemporal lobar degeneration by alkalizing reagents and inhibition of vacuolar ATPase. Capell A, Liebscher S, Fellerer K, Brouwers N, Willem M, Lammich S, Gijselinck I, Bittner T, Carlson AM, Sasse F, Kunze B, Steinmetz H, Jansen R, Dormann D, Sleegers K, Cruts M, Herms J, Van Broeckhoven C, Haass C. J Neurosci. 2011 Feb 2;31(5):1885-94. PMID: 21289198

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$ 325.00
Cat# AF3703a
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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