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RRAD (aa36-48) Antibody (internal region)

Peptide-affinity purified goat antibody

  • WB - RRAD (aa36-48) Antibody (internal region) AF3727a
    A): AF3727a (0.5 µg/ml) staining of HEK293 lysates overexpressing several HA-tagged Mouse GTPases, including Rrad (10 µg protein in RIPA buffer) and compared with an HA-specific antibody. B): AF3727a (0.5 µg/ml) staining of WT and KO lysates of Mouse Heart (100 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Data provided by Prof. D Andres, University of Kentucky College of Medicine, USA.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P55042
Other Accession NP_004156.1, 6236, 56437 (mouse), 83521 (rat)
Reactivity Mouse
Predicted Human, Rat, Pig, Dog, Cow
Host Goat
Clonality Polyclonal
Concentration 0.5 mg/ml
Isotype IgG
Calculated MW 33245 Da
Additional Information
Gene ID 6236
Other Names GTP-binding protein RAD, RAD1, Ras associated with diabetes, RRAD, RAD
Format 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsRRAD (aa36-48) Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms RAD
Function May play an important role in cardiac antiarrhythmia via the strong suppression of voltage-gated L-type Ca(2+) currents. Regulates voltage-dependent L-type calcium channel subunit alpha- 1C trafficking to the cell membrane (By similarity). Inhibits cardiac hypertrophy through the calmodulin-dependent kinase II (CaMKII) pathway. Inhibits phosphorylation and activation of CAMK2D.
Cellular Location Cell membrane.
Tissue Location Most abundantly expressed in the heart. Also found in the skeletal muscle and lung. Lesser amounts in placenta and kidney. Also detected in adipose tissue. Overexpressed in muscle of type II diabetic humans.
Research Areas
Citations (0)

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Reported variants represent identical protein: NP_004156.1, NP_001122322.1


A novel senescence-evasion mechanism involving Grap2 and Cyclin D interacting protein inactivation by Ras associated with diabetes in cancer cells under doxorubicin treatment. Lee I, Yeom SY, Lee SJ, Kang WK, Park C. Cancer Res. 2010 Jun 1;70(11):4357-65. PMID: 20460530

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$ 325.00
Cat# AF3727a
(40 western blots)
Availability: 7-10 days
Bulk Size
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