|Application ||WB, E|
|Other Accession||NP_006633.1, 10806, 76816 (mouse), 305002 (rat)|
|Predicted||Mouse, Rat, Pig, Dog|
|Calculated MW||82682 Da|
|Other Names||Serologically defined colon cancer antigen 8, Antigen NY-CO-8, Centrosomal colon cancer autoantigen protein, hCCCAP, SDCCAG8, CCCAP, NPHP10|
|Format||0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||SDCCAG8 Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Plays a role in the establishment of cell polarity and epithelial lumen formation (By similarity). May play a role in ciliogenesis.|
|Cellular Location||Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Cell junction Note=Located at the distal ends of both centrioles and colocalizes to centrosomes throughout the cell cycle|
|Tissue Location||Expressed in thymus, prostate, testis, ovary, small intestine, colon, mucosa, colon and renal cancer tumors|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Candidate exome capture identifies mutation of SDCCAG8 as the cause of a retinal-renal ciliopathy. Otto EA, Hurd TW, Airik R, Chaki M, Zhou W, Stoetzel C, Patil SB, Levy S, Ghosh AK, Murga-Zamalloa CA, van Reeuwijk J, Letteboer SJ, Sang L, Giles RH, Liu Q, Coene KL, Estrada-Cuzcano A, Collin RW, McLaughlin HM, Held S, Kasanuki JM, Ramaswami G, Conte J Nat Genet. 2010 Oct;42(10):840-50. PMID: 20835237
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