|Application ||WB, E|
|Other Accession||NP_005252.1, 2669|
|Calculated MW||33949 Da|
|Other Names||GTP-binding protein GEM, GTP-binding mitogen-induced T-cell protein, RAS-like protein KIR, GEM, KIR|
|Format||0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||GEM (aa34-46) Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Could be a regulatory protein, possibly participating in receptor-mediated signal transduction at the plasma membrane. Has guanine nucleotide-binding activity but undetectable intrinsic GTPase activity.|
|Cellular Location||Cell membrane; Peripheral membrane protein; Cytoplasmic side|
|Tissue Location||Most abundant in thymus, spleen, kidney, lung, and testis. Less abundant in heart, brain, liver and skeletal muscle|
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Reported variants represent identical protein: NP_005252.1, NP_859053.1
A systemic network for Chlamydia pneumoniae entry into human cells. Wang A, Johnston SC, Chou J, Dean D. J Bacteriol. 2010 Jun;192(11):2809-15. PMID: 20233927
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