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Synaptotagmin-3 (aa25-38) Antibody (intenal region, near N-Term)
Peptide-affinity purified goat antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| E |
|---|---|
| Primary Accession | Q9BQG1 |
| Other Accession | NP_115674.1, 84258, 20981 (mouse), 25731 (rat) |
| Predicted | Human, Mouse, Rat, Pig, Dog, Cow |
| Host | Goat |
| Clonality | Polyclonal |
| Concentration | 0.5 mg/ml |
| Isotype | IgG |
| Calculated MW | 63304 Da |
| Gene ID | 84258 |
|---|---|
| Other Names | Synaptotagmin-3, Synaptotagmin III, SytIII, SYT3 |
| Format | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | Synaptotagmin-3 (aa25-38) Antibody (intenal region, near N-Term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | SYT3 |
|---|---|
| Function | Ca(2+) sensor involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain. Ca(2+) induces binding of the C2-domains to phospholipid membranes and to assembled SNARE-complexes; both actions contribute to triggering exocytosis (By similarity). Plays a role in dendrite formation by melanocytes (PubMed:23999003). |
| Cellular Location | Cell membrane {ECO:0000250|UniProtKB:P40748}; Single-pass membrane protein. Cytoplasmic vesicle, secretory vesicle membrane; Single-pass membrane protein |
| Tissue Location | Expressed in melanocytes (PubMed:23999003). |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Reported variants represent identical protein: NP_001153801.1, NP_001153800.1, NP_115674.1. The immunizing peptide represents part of the vesicular domain.
References
Ca(2+)-dependent and -independent activities of neural and non-neural synaptotagmins. Li C, Ullrich B, Zhang JZ, Anderson RG, Brose N, Südhof TC. Nature. 1995 Jun 15;375(6532):594-9. PMID: 7791877
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