Synaptotagmin-3 (aa25-38) Antibody (intenal region, near N-Term)
Peptide-affinity purified goat antibody
|Other Accession||NP_115674.1, 84258, 20981 (mouse), 25731 (rat)|
|Predicted||Human, Mouse, Rat, Pig, Dog, Cow|
|Calculated MW||63304 Da|
|Other Names||Synaptotagmin-3, Synaptotagmin III, SytIII, SYT3|
|Format||0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||Synaptotagmin-3 (aa25-38) Antibody (intenal region, near N-Term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May be involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain or may serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis.|
|Cellular Location||Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Single-pass membrane protein|
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Provided below are standard protocols that you may find useful for product applications.
Reported variants represent identical protein: NP_001153801.1, NP_001153800.1, NP_115674.1. The immunizing peptide represents part of the vesicular domain.
Ca(2+)-dependent and -independent activities of neural and non-neural synaptotagmins. Li C, Ullrich B, Zhang JZ, Anderson RG, Brose N, Südhof TC. Nature. 1995 Jun 15;375(6532):594-9. PMID: 7791877
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