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FGF13 (isoform 1) Antibody (internal region)
Peptide-affinity purified goat antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q92913 |
| Other Accession | NP_004105.1, 2258, 14168 (mouse) |
| Reactivity | Mouse |
| Predicted | Human, Pig, Dog, Cow |
| Host | Goat |
| Clonality | Polyclonal |
| Concentration | 0.5 mg/ml |
| Isotype | IgG |
| Calculated MW | 27564 Da |
| Gene ID | 2258 |
|---|---|
| Other Names | Fibroblast growth factor 13, FGF-13, Fibroblast growth factor homologous factor 2, FHF-2, FGF13, FHF2 |
| Format | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | FGF13 (isoform 1) Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | FGF13 (HGNC:3670) |
|---|---|
| Synonyms | FHF2 |
| Function | Microtubule-binding protein which directly binds tubulin and is involved in both polymerization and stabilization of microtubules (By similarity). Through its action on microtubules, may participate in the refinement of axons by negatively regulating axonal and leading processes branching (By similarity). Plays a crucial role in neuron polarization and migration in the cerebral cortex and the hippocampus (By similarity). Regulates voltage-gated sodium channel transport and function (PubMed:15282281, PubMed:33245860, PubMed:36696443). May also play a role in MAPK signaling (By similarity). Required for the development of axonal initial segment-targeting inhibitory GABAergic synapses made by chandelier neurons (By similarity). |
| Cellular Location | [Isoform 1]: Nucleus [Isoform 3]: Cytoplasm. Nucleus [Isoform 5]: Cytoplasm {ECO:0000250|UniProtKB:P61329}. Nucleus {ECO:0000250|UniProtKB:P61329} |
| Tissue Location | Ubiquitously expressed. Predominantly expressed in the nervous system. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
This antibody is expected to recognize isoform 1 (NP_004105.1) only. Reported variants represent identical protein: NP_001132974.1, NP_001132973.1
References
Fibroblast growth factor homologous factor 2B: association with Nav1.6 and selective colocalization at nodes of Ranvier of dorsal root axons. Wittmack EK, Rush AM, Craner MJ, Goldfarb M, Waxman SG, Dib-Hajj SD. J Neurosci. 2004 Jul 28;24(30):6765-75. PMID: 15282281
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