|Application ||WB, E|
|Other Accession||NP_003035.3, 6539|
|Calculated MW||69368 Da|
|Other Names||Sodium- and chloride-dependent betaine transporter, BGT-1, Na(+)/Cl(-) betaine/GABA transporter, Solute carrier family 6 member 12, SLC6A12|
|Format||0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||SLC6A12 / BGT1 Antibody (C-Term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Transports betaine and GABA. May have a role in regulation of GABAergic transmission in the brain through the reuptake of GABA into presynaptic terminals, as well as in osmotic regulation.|
|Cellular Location||Membrane; Multi-pass membrane protein.|
|Tissue Location||Liver, heart, skeletal muscle, placenta, and a widespread distribution in the brain|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Reported variants represent identical protein: NP_001193860.1, NP_003035.3, NP_001116319.1, NP_001116320.1.
Association of SLC6A12 variants with aspirin-intolerant asthma in a Korean population. Pasaje CF, et al. Ann Hum Genet. 2010 Jul;74(4):326-34. PMID: 20597903
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