|Application ||WB, IHC, E|
|Other Accession||NP_004090.4, NP_937837.1, 2040|
|Calculated MW||31731 Da|
|Other Names||Erythrocyte band 7 integral membrane protein, Protein 7.2b, Stomatin, STOM, BND7, EPB72|
|Format||0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||Stomatin Antibody (N-Term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Regulates ion channel activity and transmembrane ion transport. Regulates ASIC2 and ASIC3 channel activity.|
|Cellular Location||Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cell membrane; Lipid-anchor; Cytoplasmic side Melanosome. Cytoplasmic vesicle. Note=Exposed on the cytoplasmic surface of the membrane. Associated with lipid rafts Concentrates preferentially in plasma membrane protrusions and in a juxta-nuclear region which may represent Golgi-derived vesicles Colocalizes with actin. Identified by mass spectrometry in melanosome fractions from stage I to stage IV|
|Tissue Location||Detected in erythrocytes (at protein level). Widely expressed.|
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Provided below are standard protocols that you may find useful for product applications.
This antibody is expected to recognize both reported isoforms (NP_004090.4; NP_937837.1).
Echinophilic proteins stomatin, sorcin, and synexin locate outside gangliosideM1 (GM1) patches in the erythrocyte membrane. Mrówczy?ska L, Salzer U, Perutková S, Igli? A, Hägerstrand H. Biochem Biophys Res Commun. 2010 Oct 22;401(3):396-400. PMID: 20858460
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