|Application ||WB, E|
|Other Accession||NP_055981.1, 23209|
|Calculated MW||41141 Da|
|Other Names||Membrane protein MLC1, MLC1, KIAA0027, WKL1|
|Format||0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||MLC1 (aa179-193) Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Regulates the response of astrocytes to hypo-osmosis by promoting calcium influx.|
|Cellular Location||Membrane; Multi-pass membrane protein. Cell membrane. Cytoplasm, perinuclear region. Endoplasmic reticulum|
|Tissue Location||Expressed in the brain, with highest levels found in the amygdala, nucleus caudatus, thalamus and hippocampus|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Reported variants represent identical protein: NP_631941.1, NP_055981.1.
Molecular mechanisms of MLC1 and GLIALCAM mutations in megalencephalic leukoencephalopathy with subcortical cysts. López-Hernández T, Sirisi S, Capdevila-Nortes X, Montolio M, Fernández-Dueñas V, Scheper GC, van der Knaap MS, Casquero P, Ciruela F, Ferrer I, Nunes V, Estévez R. Hum Mol Genet. 2011 Aug 15;20(16):3266-77. PMID: 21624973
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