MLC1 (aa179-193) Antibody (internal region)
Peptide-affinity purified goat antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
---|---|
Primary Accession | Q15049 |
Other Accession | NP_055981.1, 23209 |
Reactivity | Human |
Host | Goat |
Clonality | Polyclonal |
Concentration | 0.5 mg/ml |
Isotype | IgG |
Calculated MW | 41141 Da |
Gene ID | 23209 |
---|---|
Other Names | Membrane protein MLC1, MLC1, KIAA0027, WKL1 |
Format | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | MLC1 (aa179-193) Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | MLC1 |
---|---|
Synonyms | KIAA0027, WKL1 |
Function | Regulates the response of astrocytes to hypo-osmosis by promoting calcium influx. |
Cellular Location | Membrane; Multi-pass membrane protein. Cell membrane Cytoplasm, perinuclear region Endoplasmic reticulum |
Tissue Location | Expressed in the brain, with highest levels found in the amygdala, nucleus caudatus, thalamus and hippocampus |
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Provided below are standard protocols that you may find useful for product applications.
Background
Reported variants represent identical protein: NP_631941.1, NP_055981.1.
References
Molecular mechanisms of MLC1 and GLIALCAM mutations in megalencephalic leukoencephalopathy with subcortical cysts. López-Hernández T, Sirisi S, Capdevila-Nortes X, Montolio M, Fernández-Dueñas V, Scheper GC, van der Knaap MS, Casquero P, Ciruela F, Ferrer I, Nunes V, Estévez R. Hum Mol Genet. 2011 Aug 15;20(16):3266-77. PMID: 21624973
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