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>   home   >   Products   >   Primary Antibodies   >   Antibody Collections   >   Goat Antibodies   >   IL-17F (aa63-77) Antibody (internal region)   

IL-17F (aa63-77) Antibody (internal region)

Peptide-affinity purified goat antibody

     
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
E
Primary Accession Q96PD4
Other Accession NP_443104.1, 112744
Predicted Human
Host Goat
Clonality Polyclonal
Concentration 0.5 mg/ml
Isotype IgG
Calculated MW 18045 Da
Additional Information
Gene ID 112744
Other Names Interleukin-17F, IL-17F, Cytokine ML-1, IL17F
Format 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsIL-17F (aa63-77) Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name IL17F
Function Ligand for IL17RA and IL17RC (PubMed:17911633). The heterodimer formed by IL17A and IL17F is a ligand for the heterodimeric complex formed by IL17RA and IL17RC (PubMed:18684971). Involved in stimulating the production of other cytokines such as IL6, IL8 and CSF2, and in regulation of cartilage matrix turnover (PubMed:11591732, PubMed:11591768, PubMed:11574464). Also involved in stimulating the proliferation of peripheral blood mononuclear cells and T-cells and in inhibition of angiogenesis (PubMed:11591732). Plays a role in the induction of neutrophilia in the lungs and in the exacerbation of antigen-induced pulmonary allergic inflammation (By similarity).
Cellular Location Secreted.
Tissue Location Expressed in activated, but not resting, CD4+ T-cells and activated monocytes
Research Areas
Citations (0)

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References

Interleukin 17A and F and asthma in Saudi Arabia: gene polymorphisms and protein levels. Bazzi MD, Sultan MA, Al Tassan N, Alanazi M, Al-Amri A, Al-Hajjaj MS, Al-Muhsen S, Alba-Concepcion K, Warsy A. J Investig Allergol Clin Immunol. 2011;21(7):551-5. PMID: 22312940

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$ 325.00
Cat# AF3962a
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