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TNNT3 Antibody (C-Term)

Peptide-affinity purified goat antibody

     
  • WB - TNNT3 Antibody (C-Term) AF3966a
    AF3966a (0.01 µg/ml) staining of Human (A), Mouse (B) and Rat (C) Skeletal Muscle lysates (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
    detail
  • IHC - TNNT3 Antibody (C-Term) AF3966a
    AF3966a (5 µg/ml) staining of paraffin embedded Human Skeletal Muscle. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.
    detail
  • SPECIFICATION
  • CITATIONS
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC, E
Primary Accession P45378
Other Accession NP_006748.1, NP_001036246.1, NP_001036247.1, 7140, 21957 (mouse), 24838 (rat)
Reactivity Human, Mouse, Rat
Host Goat
Clonality Polyclonal
Concentration 0.5 mg/ml
Isotype IgG
Calculated MW 31825 Da
Additional Information
Gene ID 7140
Other Names Troponin T, fast skeletal muscle, TnTf, Beta-TnTF, Fast skeletal muscle troponin T, fTnT, TNNT3
Format 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsTNNT3 Antibody (C-Term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name TNNT3
Function Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.
Tissue Location In fetal and adult fast skeletal muscles, with a higher level expression in fetal than in adult muscle
Research Areas
Citations (0)
citation

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Background

This antibody is expected to recognize isoform 1, 2 and 4 (NP_006748.1; NP_001036246.1; NP_001036247.1).

References

A novel mutation in TNNT3 associated with Sheldon-Hall syndrome in a Chinese family with vertical talus. Zhao N, Jiang M, Han W, Bian C, Li X, Huang F, Kong Q, Li J. Eur J Med Genet. 2011 May-Jun;54(3):351-3. PMID: 21402185

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$ 341.00
Cat# AF3966a
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