|Application ||IHC, E|
|Other Accession||NP_071325.2, NP_602297.1, 10861|
|Calculated MW||75016 Da|
|Other Names||Sulfate anion transporter 1, SAT-1, Solute carrier family 26 member 1, SLC26A1, SAT1|
|Format||0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||SLC26A1 / SAT-1 Antibody (C-Term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||High affinity uptake of sulfate. Accepts oxalate, but not succinate as a cosubstrate. Mediates sulfate and oxalate transport.|
|Cellular Location||Membrane; Multi-pass membrane protein|
|Tissue Location||Expressed most abundantly in the kidney and liver, with lower levels in the pancreas, testis, brain, small intestine, colon, and lung.|
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Provided below are standard protocols that you may find useful for product applications.
This antibody is expected to recognize reported isoform a (NP_071325.2) only. Reported variants represent identical protein: NP_998778.1, NP_071325.2
Glyoxylate is a substrate of the sulfate-oxalate exchanger, sat-1, and increases its expression in HepG2 cells. Schnedler N, Burckhardt G, Burckhardt BC. Journal of hepatology 2011 Mar 54 (3): 513-20. PMID: 21093948
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