|Application ||WB, E|
|Other Accession||NP_065079.1, 57084, 140919 (mouse), 84487 (rat)|
|Predicted||Mouse, Rat, Pig, Dog, Cow|
|Calculated MW||64392 Da|
|Other Names||Vesicular glutamate transporter 2, VGluT2, Differentiation-associated BNPI, Differentiation-associated Na(+)-dependent inorganic phosphate cotransporter, Solute carrier family 17 member 6, SLC17A6, DNPI, VGLUT2|
|Format||0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||VGLUT2 (aa521-534) Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Mediates the uptake of glutamate into synaptic vesicles at presynaptic nerve terminals of excitatory neural cells. May also mediate the transport of inorganic phosphate.|
|Cellular Location||Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane. Membrane; Multi-pass membrane protein. Cell junction, synapse, synaptosome|
|Tissue Location||Predominantly expressed in adult brain. Expressed in amygdala, caudate nucleus, cerebral cortex, frontal lobe, hippocampus, medulla, occipital lobe, putamen, spinal cord, substantia nigra, subthalamic nucleus, temporal lobe and thalamus|
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Provided below are standard protocols that you may find useful for product applications.
Glutamatergic and GABAergic innervation of human gonadotropin-releasing hormone-I neurons. Hrabovszky E, Molnár CS, Nagy R, Vida B, Borsay BÁ, Rácz K, Herczeg L, Watanabe M, Kalló I, Liposits Z. Endocrinology 2012 Jun 153 (6): 2766-76. PMID: 22510271
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