|Application ||WB, E|
|Other Accession||NP_002513.2, 4884|
|Calculated MW||47122 Da|
|Other Names||Neuronal pentraxin-1, NP1, Neuronal pentraxin I, NP-I, NPTX1|
|Format||0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||neuronal pentraxin 1 Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May be involved in mediating uptake of synaptic material during synapse remodeling or in mediating the synaptic clustering of AMPA glutamate receptors at a subset of excitatory synapses.|
|Cellular Location||Cytoplasmic vesicle, secretory vesicle|
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Neuronal pentraxin 1 contributes to the neuronal damage evoked by amyloid-beta and is overexpressed in dystrophic neurites in Alzheimer's brain. Abad MA, Enguita M, DeGregorio-Rocasolano N, Ferrer I, Trullas R. J Neurosci. 2006 Dec 6;26(49):12735-47. PMID: 17151277
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