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neuronal pentraxin 1 Antibody (internal region)

Peptide-affinity purified goat antibody

     
  • WB - neuronal pentraxin 1 Antibody (internal region) AF4024a
    AF4024a (1 µg/ml) staining of Human Frontal Cortex lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
    detail
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q15818
Other Accession NP_002513.2, 4884
Reactivity Human
Host Goat
Clonality Polyclonal
Concentration 0.5 mg/ml
Isotype IgG
Calculated MW 47122 Da
Additional Information
Gene ID 4884
Other Names Neuronal pentraxin-1, NP1, Neuronal pentraxin I, NP-I, NPTX1
Format 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Precautionsneuronal pentraxin 1 Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name NPTX1
Function May be involved in mediating uptake of synaptic material during synapse remodeling or in mediating the synaptic clustering of AMPA glutamate receptors at a subset of excitatory synapses.
Cellular Location Secreted. Cytoplasmic vesicle, secretory vesicle {ECO:0000269|PubMed:34788392, ECO:0000305}. Endoplasmic reticulum {ECO:0000269|PubMed:34788392, ECO:0000305}
Research Areas
Citations (0)
citation

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References

Neuronal pentraxin 1 contributes to the neuronal damage evoked by amyloid-beta and is overexpressed in dystrophic neurites in Alzheimer's brain. Abad MA, Enguita M, DeGregorio-Rocasolano N, Ferrer I, Trullas R. J Neurosci. 2006 Dec 6;26(49):12735-47. PMID: 17151277

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$ 341.00
Cat# AF4024a
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