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CD44 Antibody (internal region)

Peptide-affinity purified goat antibody

  • WB - CD44 Antibody (internal region) AF4032a
    E12255 (0.03 µg/ml) staining of U-2 OS lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P16070
Other Accession NP_000601.3, NP_001001389.1, NP_001001390.1, NP_001001391.1, NP_001001392.1, NP_001189484.1, NP_001189485.1, NP_001189486.1, 960
Reactivity Human
Host Goat
Clonality Polyclonal
Concentration 0.5 mg/ml
Isotype IgG
Calculated MW 81538 Da
Additional Information
Gene ID 960
Other Names CD44 antigen, CDw44, Epican, Extracellular matrix receptor III, ECMR-III, GP90 lymphocyte homing/adhesion receptor, HUTCH-I, Heparan sulfate proteoglycan, Hermes antigen, Hyaluronate receptor, Phagocytic glycoprotein 1, PGP-1, Phagocytic glycoprotein I, PGP-I, CD44, CD44, LHR, MDU2, MDU3, MIC4
Format 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCD44 Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CD44
Synonyms LHR, MDU2, MDU3, MIC4
Function Receptor for hyaluronic acid (HA). Mediates cell-cell and cell-matrix interactions through its affinity for HA, and possibly also through its affinity for other ligands such as osteopontin, collagens, and matrix metalloproteinases (MMPs). Adhesion with HA plays an important role in cell migration, tumor growth and progression. In cancer cells, may play an important role in invadopodia formation. Also involved in lymphocyte activation, recirculation and homing, and in hematopoiesis. Altered expression or dysfunction causes numerous pathogenic phenotypes. Great protein heterogeneity due to numerous alternative splicing and post-translational modification events.
Cellular Location Cell membrane; Single-pass type I membrane protein. Note=Colocalizes with actin in membrane protrusions at wounding edges.
Tissue Location Isoform 10 (epithelial isoform) is expressed by cells of epithelium and highly expressed by carcinomas Expression is repressed in neuroblastoma cells
Research Areas
Citations (0)

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This antibody is expected to recognize reported isoforms 1, 2, 3, 4, 6, 7, 8 (NP_000601.3; NP_001001389.1; NP_001001390.1; NP_001001391.1; NP_001189484.1; NP_001189485.1; NP_001189486.1).


Moesin is a glioma progression marker that induces proliferation and Wnt/?-catenin pathway activation via interaction with CD44. Zhu X, Morales FC, Agarwal NK, Dogruluk T, Gagea M, Georgescu MM. Cancer research 2013 Feb 73 (3): 1142-55. PMID: 23221384

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$ 325.00
Cat# AF4032a
(40 western blots)
Availability: 7-10 days
Bulk Size
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