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MUNC18C Antibody (internal region)

Peptide-affinity purified goat antibody

  • WB - MUNC18C Antibody (internal region) AF4063a
    AF4063a (0.3 µg/ml) staining of Rat Spleen lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O00186
Other Accession NP_009200.2, 6814, 20912 (mouse), 114095 (rat)
Reactivity Mouse, Rat
Predicted Human, Pig, Dog
Host Goat
Clonality Polyclonal
Concentration 0.5 mg/ml
Isotype IgG
Calculated MW 67764 Da
Additional Information
Gene ID 6814
Other Names Syntaxin-binding protein 3, Platelet Sec1 protein, PSP, Protein unc-18 homolog 3, Unc18-3, Protein unc-18 homolog C, Unc-18C, STXBP3
Format 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsMUNC18C Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Function Together with STX4 and VAMP2, may play a role in insulin-dependent movement of GLUT4 and in docking/fusion of intracellular GLUT4-containing vesicles with the cell surface in adipocytes.
Cellular Location Cytoplasm, cytosol. Cell membrane. Note=In platelets, predominantly cytosolic. Low amounts membrane-associated
Tissue Location Megakaryocytes and platelets.
Research Areas
Citations (0)

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Munc18c phosphorylation by the insulin receptor links cell signaling directly to SNARE exocytosis. Jewell JL, Oh E, Ramalingam L, Kalwat MA, Tagliabracci VS, Tackett L, Elmendorf JS, Thurmond DC. The Journal of cell biology 2011 Apr 193 (1): 185-99. PMID: 21444687

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$ 325.00
Cat# AF4063a
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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