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Peptide-affinity purified goat antibody
- SPECIFICATION
- CITATIONS
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- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | P18827 |
| Other Accession | NP_002988.3, 6382 |
| Reactivity | Human |
| Host | Goat |
| Clonality | Polyclonal |
| Concentration | 0.5 mg/ml |
| Isotype | IgG |
| Calculated MW | 32462 Da |
| Gene ID | 6382 |
|---|---|
| Other Names | Syndecan-1, SYND1, CD138, SDC1, SDC |
| Format | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | syndecan 1 / CD138 Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | SDC1 |
|---|---|
| Synonyms | SDC |
| Function | Cell surface proteoglycan that bears both heparan sulfate and chondroitin sulfate and that links the cytoskeleton to the interstitial matrix. Regulates exosome biogenesis in concert with SDCBP and PDCD6IP (PubMed:22660413). |
| Cellular Location | Membrane; Single-pass type I membrane protein. Secreted. Secreted, exosome. Note=Shedding of the ectodomain produces a soluble form. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Reported variants represent identical protein: NP_001006947.1, NP_002988.3.
References
Removal of syndecan-1 promotes TRAIL-induced apoptosis in myeloma cells. Wu YH, Yang CY, Chien WL, Lin KI, Lai MZ. Journal of immunology (Baltimore, Md. : 1950) 2012 Mar 188 (6): 2914-21. PMID: 22308310
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