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SERPINB1 (aa130-143) Antibody (internal region)

Peptide-affinity purified goat antibody

     
  • WB - SERPINB1 (aa130-143) Antibody (internal region) AF4090a
    AF4090a (0.5 µg/ml) staining of Human Placenta lysate (35 µg protein in RIPA buffer) with (B) and without (A) blocking with the immunizing peptide. Primary incubation was 1 hour. Detected by chemiluminescence.
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession P30740
Other Accession NP_109591.1, 1992
Reactivity Human
Host Goat
Clonality Polyclonal
Concentration 0.5 mg/ml
Isotype IgG
Calculated MW 42742 Da
Additional Information
Gene ID 1992
Other Names Leukocyte elastase inhibitor, LEI, Monocyte/neutrophil elastase inhibitor, EI, M/NEI, Peptidase inhibitor 2, PI-2, Serpin B1, SERPINB1, ELANH2, MNEI, PI2
Format 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsSERPINB1 (aa130-143) Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SERPINB1
Synonyms ELANH2, MNEI, PI2
Function Regulates the activity of the neutrophil proteases elastase, cathepsin G, proteinase-3, chymase, chymotrypsin, and kallikrein-3. Also functions as a potent intracellular inhibitor of granzyme H.
Cellular Location Cytoplasm. Cytoplasmic granule
Research Areas
Citations (0)

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References

SerpinB1 in cystic fibrosis airway fluids: quantity, molecular form and mechanism of elastase inhibition. Cooley J, Sontag MK, Accurso FJ, Remold-O'Donnell E. The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2011 May 37 (5): 1083-90. PMID: 20817705

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$ 335.00
Cat# AF4090a
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