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CLIC1 / NCC27 Antibody (internal region)

Peptide-affinity purified goat antibody

  • WB - CLIC1 / NCC27 Antibody (internal region) AF4092a
    AF4091a (2 µg/ml) staining of U937 lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O00299
Other Accession NP_001279.2, 1192, 114584 (mouse), 406864 (rat)
Reactivity Human
Predicted Mouse, Rat, Pig, Dog, Cow
Host Goat
Clonality Polyclonal
Concentration 0.5 mg/ml
Isotype IgG
Calculated MW 26923 Da
Additional Information
Gene ID 1192
Other Names Chloride intracellular channel protein 1, Chloride channel ABP, Nuclear chloride ion channel 27, NCC27, Regulatory nuclear chloride ion channel protein, hRNCC, CLIC1, G6, NCC27
Format 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCLIC1 / NCC27 Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CLIC1
Synonyms G6, NCC27
Function Can insert into membranes and form chloride ion channels. Channel activity depends on the pH. Membrane insertion seems to be redox-regulated and may occur only under oxydizing conditions. Involved in regulation of the cell cycle.
Cellular Location Nucleus. Nucleus membrane; Single-pass membrane protein. Cytoplasm. Cell membrane; Single-pass membrane protein. Note=Mostly in the nucleus including in the nuclear membrane. Small amount in the cytoplasm and the plasma membrane Exists both as soluble cytoplasmic protein and as membrane protein with probably a single transmembrane domain
Tissue Location Expression is prominent in heart, placenta, liver, kidney and pancreas.
Research Areas
Citations (0)

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Transmembrane extension and oligomerization of the CLIC1 chloride intracellular channel protein upon membrane interaction. Goodchild SC, Angstmann CN, Breit SN, Curmi PM, Brown LJ. Biochemistry 2011 Dec 50 (50): 10887-97. PMID: 22082111

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$ 325.00
Cat# AF4092a
(40 western blots)
Availability: 7-10 days
Bulk Size
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