|Application ||WB, IHC, E|
|Other Accession||NP_002128.1, NP_112533.1, 3181, 53379 (mouse), 362361 (rat)|
|Predicted||Rat, Pig, Dog, Cow|
|Calculated MW||37430 Da|
|Other Names||Heterogeneous nuclear ribonucleoproteins A2/B1, hnRNP A2/B1, HNRNPA2B1, HNRPA2B1|
|Format||0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||HNRNPA2B1 Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Involved with pre-mRNA processing. Forms complexes (ribonucleosomes) with at least 20 other different hnRNP and heterogeneous nuclear RNA in the nucleus.|
|Cellular Location||Nucleus, nucleoplasm. Cytoplasm. Note=Localized in cytoplasmic mRNP granules containing untranslated mRNAs. Component of ribonucleosomes. Predominantly nucleoplasmic, however isoform A2 is also found in the cytoplasm of cells in some tissues. Not found in the nucleolus|
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Provided below are standard protocols that you may find useful for product applications.
This antibody is expected to recognize both reported isoforms (NP_002128.1; NP_112533.1).
Interaction of hnRNPA1/A2 and DAZAP1 with an Alu-derived intronic splicing enhancer regulates ATM aberrant splicing. Pastor T, Pagani F. PloS one 2011 6 (8): e23349. PMID: 21858080
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