|Application ||WB, E|
|Other Accession||NP_055139.4, NP_001161067.1, 23600|
|Calculated MW||42387 Da|
|Other Names||Alpha-methylacyl-CoA racemase, 22.214.171.124, 2-methylacyl-CoA racemase, AMACR|
|Format||0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||AMACR (aa312-326) Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Racemization of 2-methyl-branched fatty acid CoA esters. Responsible for the conversion of pristanoyl-CoA and C27-bile acyl-CoAs to their (S)-stereoisomers.|
|Cellular Location||Peroxisome. Mitochondrion|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
This antibody is expected to recognize isoform 1 (NP_055139.4) and isoform 3 (NP_001161067.1).
High-throughput screen identifies novel inhibitors of cancer biomarker a-methylacyl coenzyme A racemase (AMACR/P504S). Wilson BA, Wang H, Nacev BA, Mease RC, Liu JO, Pomper MG, Isaacs WB. Molecular cancer therapeutics 2011 May 10 (5): 825-38. PMID: 21441411
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