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Goat Anti-BDNF Antibody (internal region)

Purified Goat Polyclonal Antibody

  • IF - Goat Anti-BDNF Antibody (internal region) AF4155a
    AF4155a (1 µg/ml) staining of PFA-perfused cryosection of Mouse sciatic nerve (left) and injured sciatic nerve (right). Alexa 488-staining. Data obtained from Simon Glerup, Department of BiomedicineAarhus University, Denmark.
  • IF - Goat Anti-BDNF Antibody (internal region) AF4155a
    AF4155a (5ug/ml) staining of paraffin embedded Rat Cerebral Cortex (A) and Rat Hippocampus (B), CRY-staining with DAPI nuclear counter stain in blue. Antigen retrieval with citrate buffer pH 6 at 95-98C.
  • IHC-P - Goat Anti-BDNF Antibody (internal region) AF4155a
    AF4155a (5ug/ml) staining of paraffin embedded Rat Cerebral Cortex. Antigen retrieval with citrate buffer pH 6 at 95-98C, DAB-staining.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P23560
Other Accession NP_001700.2, NP_001700.2, NP_733928.1, NP_733929.1, NP_733930.1, NP_733931.1
Reactivity Human, Mouse, Rat
Predicted Human, Mouse, Rat, Dog
Host Goat
Clonality Polyclonal
Concentration 0.5
Calculated MW 27818 Da
Additional Information
Gene ID 627
Other Names BDNF ; brain-derived neurotrophic factor; MGC34632; neurotrophin
Format Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
Immunogen Peptide with sequence ETKCNPMGYTKE, from the internal region of the protein sequence according to NP_001700.2; NP_001700.2; NP_733928.1; NP_733929.1; NP_733930.1; NP_733931.1.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGoat Anti-BDNF Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Function During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including long-term potentiation (LTP), long-term depression (LTD), certain forms of short-term synaptic plasticity, as well as homeostatic regulation of intrinsic neuronal excitability.
Cellular Location Secreted.
Tissue Location Brain. Highly expressed in hippocampus, amygdala, cerebral cortex and cerebellum. Also expressed in heart, lung, skeletal muscle, testis, prostate and placenta
Research Areas
Citations (0)

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BDNF induces transport of PSD-95 to dendrites through PI3K-AKT signaling after NMDA receptor activation. Yoshii A, Constantine-Paton M. Nat Neurosci. 2007 Jun;10(6):702-711. Epub 2007 May 21.

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$ 325.00
Cat# AF4155a
(40 western blots)
Availability: 7-10 days
Bulk Size
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