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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   Goat Anti-NFATC3 / NFAT4 Antibody (internal region (near N Terminus))   

Goat Anti-NFATC3 / NFAT4 Antibody (internal region (near N Terminus))

Purified Goat Polyclonal Antibody

  • WB - Goat Anti-NFATC3 / NFAT4 Antibody (internal region (near N Terminus)) AF4162a
    AF4162a (0.03 µg/ml) staining of Jurkat nuclear lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q12968
Other Accession NP_775188.1, NP_004546.1, NP_775186.1, NP_775187.1
Reactivity Human
Predicted Human, Cow, Dog
Host Goat
Clonality Polyclonal
Concentration 0.5
Calculated MW 115594 Da
Additional Information
Gene ID 4775
Other Names NFATC3; nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3; NFAT4; NFATX; T cell transcription factor NFAT4; nuclear factor of activated T-cells c3 isoform IE-Xa; nuclear factor of activated T-cells, cytoplasmic 3
Format Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
Immunogen Peptide with sequence C-HQELDAHEDDLQIN, from the internal region (near N Terminus) of the protein sequence according to NP_775188.1; NP_004546.1; NP_775186.1; NP_775187.1.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGoat Anti-NFATC3 / NFAT4 Antibody (internal region (near N Terminus)) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms NFAT4
Function Acts as a regulator of transcriptional activation. Plays a role in the inducible expression of cytokine genes in T-cells, especially in the induction of the IL-2.
Cellular Location Cytoplasm. Nucleus. Note=Cytoplasmic for the phosphorylated form and nuclear after activation that is controlled by calcineurin-mediated dephosphorylation. Rapid nuclear exit of NFATC is thought to be one mechanism by which cells distinguish between sustained and transient calcium signals The subcellular localization of NFATC plays a key role in the regulation of gene transcription
Tissue Location Isoform 1 is predominantly expressed in thymus and is also found in peripheral blood leukocytes and kidney Isoform 2 is predominantly expressed in skeletal muscle and is also found in thymus, kidney, testis, spleen, prostate, ovary, small intestine, heart, placenta and pancreas. Isoform 3 is expressed in thymus and kidney. Isoform 4 is expressed in thymus and skeletal muscle
Research Areas
Citations (0)

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A constitutively nuclear form of NFATx shows efficient transactivation activity and induces differentiation of CD4(+)CD8(+) T cells. Amasaki Y, Adachi S, Ishida Y, Iwata M, Arai N, Arai K, Miyatake S, J. Biol. Chem. 2002 Jul 277 (28): 25640-8.

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$ 325.00
Cat# AF4162a
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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