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Goat Anti-SOX11 Antibody (C Terminus)
Purified Goat Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| E |
|---|---|
| Primary Accession | P35716 |
| Other Accession | 20666(mouse), 84046(rat), NP_003099.1 |
| Predicted | Human, Mouse, Rat, Pig, Cow, Xenopus |
| Host | Goat |
| Clonality | Polyclonal |
| Concentration | 0.5 |
| Calculated MW | 46679 Da |
| Gene ID | 6664 |
|---|---|
| Other Names | Sox11; SRY (sex determining region Y)-box 11 |
| Format | Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing. |
| Immunogen | Peptide with sequence C-DWLEANFSDLVFTY, from the C Terminus of the protein sequence according to NP_003099.1. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | Goat Anti-SOX11 Antibody (C Terminus) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | SOX11 |
|---|---|
| Function | Transcription factor that acts as a transcriptional activator (PubMed:24886874, PubMed:26543203). Binds cooperatively with POU3F2/BRN2 or POU3F1/OCT6 to gene promoters, which enhances transcriptional activation (By similarity). Acts as a transcriptional activator of TEAD2 by binding to its gene promoter and first intron (By similarity). Plays a redundant role with SOX4 and SOX12 in cell survival of developing tissues such as the neural tube, branchial arches and somites, thereby contributing to organogenesis (By similarity). |
| Cellular Location | Nucleus {ECO:0000255|PROSITE-ProRule:PRU00267, ECO:0000269|PubMed:24886874, ECO:0000269|PubMed:35938035} |
| Tissue Location | Expressed primarily in the brain and heart, with low expression in the kidney, pancreas and muscle |
Research Areas
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Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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$ 216.00
Cat# AF4163a
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