Goat Anti-Stap2 Antibody (C Terminus)
Purified Goat Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
---|---|
Primary Accession | Q8R0L1 |
Other Accession | 106766(mouse), 363334(rat), NP_666046.1 |
Reactivity | Mouse |
Predicted | Mouse, Rat, Cow |
Host | Goat |
Clonality | Polyclonal |
Concentration | 0.5 |
Calculated MW | 45802 Da |
Gene ID | 106766 |
---|---|
Other Names | Stap2; signal transducing adaptor family member 2; AW049765; STAP-2; signal-transducing adaptor protein 2; signal-transducing adaptor protein-2 |
Format | Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing. |
Immunogen | Peptide with sequence C-EEKLQKRRALEH, from the C Terminus of the protein sequence according to NP_666046.1. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | Goat Anti-Stap2 Antibody (C Terminus) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | Stap2 |
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Function | Substrate of protein kinase PTK6 (By similarity). May play a regulatory role in the acute-phase response in systemic inflammation and may modulate STAT3 activity. |
Cellular Location | Cytoplasm. Membrane; Peripheral membrane protein. Note=The translocation to the membranes occurs in response to EGF when the protein is overexpressed in fibroblastic cells |
Tissue Location | Widely expressed.. |
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Provided below are standard protocols that you may find useful for product applications.
References
STAP-2 regulates c-Fms/M-CSF receptor signaling in murine macrophage Raw 264.7 cells. Ikeda O, Sekine Y, Kakisaka M, Tsuji S, Muromoto R, Ohbayashi N, Oritani K,
Yoshimura A, Matsuda T. Biochem Biophys Res Commun. 2007 Jul 6;358(3):931-7.
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