|Application ||WB, E|
|Other Accession||106766(mouse), 363334(rat), NP_666046.1|
|Predicted||Mouse, Rat, Cow|
|Calculated MW||45802 Da|
|Other Names||Stap2; signal transducing adaptor family member 2; AW049765; STAP-2; signal-transducing adaptor protein 2; signal-transducing adaptor protein-2|
|Format||Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.|
|Immunogen||Peptide with sequence C-EEKLQKRRALEH, from the C Terminus of the protein sequence according to NP_666046.1.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||Goat Anti-Stap2 Antibody (C Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Substrate of protein kinase PTK6 (By similarity). May play a regulatory role in the acute-phase response in systemic inflammation and may modulate STAT3 activity.|
|Cellular Location||Cytoplasm. Membrane; Peripheral membrane protein. Note=The translocation to the membranes occurs in response to EGF when the protein is overexpressed in fibroblastic cells|
|Tissue Location||Widely expressed.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
STAP-2 regulates c-Fms/M-CSF receptor signaling in murine macrophage Raw 264.7 cells. Ikeda O, Sekine Y, Kakisaka M, Tsuji S, Muromoto R, Ohbayashi N, Oritani K,
Yoshimura A, Matsuda T. Biochem Biophys Res Commun. 2007 Jul 6;358(3):931-7.
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