|Application ||IHC, E|
|Other Accession||21961(mouse), 301509(rat), NP_072174.3|
|Predicted||Human, Mouse, Rat, Cow|
|Calculated MW||185701 Da|
|Other Names||TNS1; tensin 1; DKFZp586K0617; MGC88584; MST091; MST122; MST127; MSTP122; MSTP127; MXRA6; TNS; Matrix-remodelling-associated protein 6; OTTHUMP00000207627; OTTHUMP00000207628; matrix-remodelling associated 6; tensin-1|
|Format||Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.|
|Immunogen||Peptide with sequence C-QYENQSPEATSPR, from the internal region of the protein sequence according to NP_072174.3.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||Goat Anti-Tensin 1 Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Involved in fibrillar adhesion formation. May be involved in cell migration, cartilage development and in linking signal transduction pathways to the cytoskeleton.|
|Cellular Location||Cell surface. Cell junction, focal adhesion Cytoplasm, cytoskeleton Note=Localized at cell periphery preferentially to fibrillar adhesions than focal adhesions. Translocates from the cell edge to cell center in an ITGB1BP1-dependent manner|
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Provided below are standard protocols that you may find useful for product applications.
Molecular characterization of human tensin. Chen H, Ishii A, Wong WK, Chen LB, Lo SH. Biochem J. 2000 Oct 15;351 Pt 2:403-11.
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