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>   home   >   Products   >   Primary Antibodies   >   Neuroscience   >   Goat Anti-Galectin 3 Antibody (internal region)   

Goat Anti-Galectin 3 Antibody (internal region)

Purified Goat Polyclonal Antibody

     
  • WB - Goat Anti-Galectin 3 Antibody (internal region) AF4190a
    AF4190a (0.3 µg/ml) staining of Human (A) and Mouse (B) Colon lysates (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession P17931
Other Accession NP_002297.2
Reactivity Human, Mouse
Predicted Human, Mouse, Rat
Host Goat
Clonality Polyclonal
Concentration 0.5
Calculated MW 26152 Da
Additional Information
Gene ID 3958
Other Names LGALS3; lectin, galactoside-binding, soluble, 3 ; CBP35; GAL3; GALBP; GALIG; LGALS2; MAC2 ; IgE-binding protein; MAC-2 antigen; carbohydrate-binding protein 35; galactose-specific lectin 3; galectin 3; galectin-3 internal gene; laminin-binding protein; lectin, galactoside-binding, soluble, 3 (galectin 3)
Format Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
Immunogen Peptide with sequence CNTKLDNNWGREERQ, from the internal region of the protein sequence according to NP_002297.2.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGoat Anti-Galectin 3 Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name LGALS3
Synonyms MAC2
Function Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis (By similarity). In the nucleus: acts as a pre-mRNA splicing factor. Involved in acute inflammatory responses including neutrophil activation and adhesion, chemoattraction of monocytes macrophages, opsonization of apoptotic neutrophils, and activation of mast cells.
Cellular Location Cytoplasm. Nucleus. Secreted. Note=Secreted by a non-classical secretory pathway and associates with the cell surface
Tissue Location A major expression is found in the colonic epithelium. It is also abundant in the activated macrophages Expressed in fetal membranes.
Research Areas
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References

Increased galectin-3 expression and intraepithelial neutrophils in small airways in severe chronic obstructive pulmonary disease. Pilette C, Colinet B, Kiss R, Andre S, Kaltner H, Gabius HJ, Delos M, Vaerman JP, Decramer M, Sibille Y. Eur Respir J. 2007 Jan 24; [Epub ahead of print]

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$ 325.00
Cat# AF4190a
Size:
Quantity:
(40 western blots)
Availability: 7-10 days
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