|Calculated MW||45847 Da|
|Other Names||ACR; acrosin; acrosin light and heavy chain prepropeptide; preproacrosin; proacrosin|
|Format||Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.|
|Immunogen||Peptide with sequence C-HEKYNSATEGND, from the internal region of the protein sequence according to NP_001088.2.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||Goat Anti-Acrosin heavy chain Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Acrosin is the major protease of mammalian spermatozoa. It is a serine protease of trypsin-like cleavage specificity, it is synthesized in a zymogen form, proacrosin and stored in the acrosome.|
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Provided below are standard protocols that you may find useful for product applications.
DNA immunization against proacrosin impairs fertility in male mice. García L, Veiga MF, Lustig L, Vazquez-Levin MH, Veaute C. American journal of reproductive immunology (New York, N.Y. : 1989) 2012 Jul 68 (1): 56-67.
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