Goat Anti-FCRL1 Antibody (C Terminus)
Purified Goat Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
---|---|
Primary Accession | Q96LA6 |
Other Accession | NP_443170.1, NP_001152870.1 |
Reactivity | Human |
Predicted | Human |
Host | Goat |
Clonality | Polyclonal |
Concentration | 0.5 |
Calculated MW | 46936 Da |
Gene ID | 115350 |
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Other Names | FCRL1; Fc receptor-like 1; CD307a; FCRH1; IFGP1; IRTA5; Fc receptor-like protein 1; IFGP family protein 1; fc receptor homolog 1; fcR-like protein 1; hIFGP1; immune receptor translocation-associated protein 5; immunoglobulin superfamily Fc receptor, gp42 |
Format | Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing. |
Immunogen | Peptide with sequence C-SRLRKANITDVD, from the C Terminus of the protein sequence according to NP_443170.1; NP_001152870.1. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | Goat Anti-FCRL1 Antibody (C Terminus) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | FCRL1 |
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Synonyms | FCRH1, IFGP1, IRTA5 |
Function | May function as an activating coreceptor in B-cells. May function in B-cells activation and differentiation. |
Cellular Location | Cell membrane; Single-pass type I membrane protein |
Tissue Location | Primarily expressed in secondary lymphoid tissues by mature subsets of B-cells. Detected in spleen, lymph node, heart, skeletal muscle, kidney, liver and placenta. Specifically expressed by mature B lineage cells with higher expression in naive versus memory B- cells (at protein level). |
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Provided below are standard protocols that you may find useful for product applications.
References
FCRL1 on chronic lymphocytic leukemia, hairy cell leukemia, and B-cell non-Hodgkin lymphoma as a target of immunotoxins. Du X, Nagata S, Ise T, Stetler-Stevenson M, Pastan I. Blood 2008 Jan 111 (1): 338-43.
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