|Application ||WB, E|
|Other Accession||NP_443170.1, NP_001152869.1, NP_001152870.1|
|Calculated MW||46936 Da|
|Other Names||FCRL1; Fc receptor-like 1; CD307a; FCRH1; IFGP1; IRTA5; Fc receptor-like protein 1; IFGP family protein 1; fc receptor homolog 1; fcR-like protein 1; hIFGP1; immune receptor translocation-associated protein 5; immunoglobulin superfamily Fc receptor, gp42|
|Format||Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.|
|Immunogen||Peptide with sequence C-TAEYEIPSVRESD, from the internal region of the protein sequence according to NP_443170.1; NP_001152869.1; NP_001152870.1.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||Goat Anti-FCRL1 Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||FCRH1, IFGP1, IRTA5|
|Function||May function as an activating coreceptor in B-cells. May function in B-cells activation and differentiation.|
|Cellular Location||Cell membrane; Single-pass type I membrane protein|
|Tissue Location||Primarily expressed in secondary lymphoid tissues by mature subsets of B-cells. Detected in spleen, lymph node, heart, skeletal muscle, kidney, liver and placenta Specifically expressed by mature B lineage cells with higher expression in naive versus memory B-cells (at protein level)|
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Provided below are standard protocols that you may find useful for product applications.
FCRL1 on chronic lymphocytic leukemia, hairy cell leukemia, and B-cell non-Hodgkin lymphoma as a target of immunotoxins. Du X, Nagata S, Ise T, Stetler-Stevenson M, Pastan I. Blood 2008 Jan 111 (1): 338-43.
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