|Application ||WB, E|
|Calculated MW||29618 Da|
|Other Names||EGFL7; EGF-like-domain, multiple 7; NEU1; RP11-251M1.2; VE-STATIN; ZNEU1; EGF-like protein 7; NOTCH4-like protein; epidermal growth factor-like protein 7; multiple EGF-like domains protein 7; multiple epidermal growth factor-like domains protein 7; vascul|
|Format||Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.|
|Immunogen||Peptide with sequence C-HGDPVSESFVQR, from the internal region of the protein sequence according to NP_057299.1.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||Goat Anti-EGFL7 Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Regulates vascular tubulogenesis in vivo. Inhibits platelet-derived growth factor (PDGF)-BB-induced smooth muscle cell migration and promotes endothelial cell adhesion to the extracellular matrix and angiogenesis.|
|Cellular Location||Secreted, extracellular space|
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Provided below are standard protocols that you may find useful for product applications.
Egfl7 promotes tumor escape from immunity by repressing endothelial cell activation. Delfortrie S, Pinte S, Mattot V, Samson C, Villain G, Caetano B, Lauridant-Philippin G, Baranzelli MC, Bonneterre J, Trottein F, Faveeuw C, Soncin F. Cancer research 2011 Dec 71 (23): 7176-86.
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