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>   home   >   Products   >   Primary Antibodies   >   Immunology   >   Goat Anti-U-PAR / CD87 Antibody (internal region)   

Goat Anti-U-PAR / CD87 Antibody (internal region)

Purified Goat Polyclonal Antibody

  • WB - Goat Anti-U-PAR / CD87 Antibody (internal region) AF4261a
    AF4261a (1 µg/ml) staining of U251 lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q03405
Other Accession NP_002650.1, NP_001005376.1, NP_001005377.1
Reactivity Human
Predicted Human
Host Goat
Clonality Polyclonal
Concentration 0.5
Calculated MW 36978 Da
Additional Information
Gene ID 5329
Other Names PLAUR; plasminogen activator, urokinase receptor; CD87; U-PAR; UPAR; URKR; monocyte activation antigen Mo3; u-plasminogen activator receptor form 2; urokinase plasminogen activator surface receptor; urokinase-type plasminogen activator (uPA) receptor
Format Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
Immunogen Peptide with sequence C-RTGLKITSLTE , from the internal region of the protein sequence according to NP_002650.1; NP_001005376.1; NP_001005377.1.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGoat Anti-U-PAR / CD87 Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms MO3, UPAR
Function Acts as a receptor for urokinase plasminogen activator. Plays a role in localizing and promoting plasmin formation. Mediates the proteolysis-independent signal transduction activation effects of U-PA. It is subject to negative-feedback regulation by U-PA which cleaves it into an inactive form.
Cellular Location Cell membrane. Cell projection, invadopodium membrane. Note=Colocalized with FAP (seprase) preferentially at the cell surface of invadopodia membrane in a cytoskeleton-, integrin- and vitronectin-dependent manner Isoform 2: Secreted.
Tissue Location Expressed in neurons of the rolandic area of the brain (at protein level). Expressed in the brain
Research Areas
Citations (0)

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Targeting uPAR with antagonistic recombinant human antibodies in aggressive breast cancer. LeBeau AM, Duriseti S, Murphy ST, Pepin F, Hann B, Gray JW, VanBrocklin HF, Craik CS. Cancer research 2013 Apr 73 (7): 2070-81.

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$ 325.00
Cat# AF4261a
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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