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Anti-S100B Antibody (Internal)

  • WB - Anti-S100B Antibody (Internal) AF4282a
    Antibody (1 µg/ml) staining of Human Olfactory Bulb (A) and Cerebellum (B) lysates (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P04271
Other Accession 6285, NP_006263.1
Reactivity Human
Predicted Human
Calculated MW 10713 Da
Additional Information
Gene ID 6285
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsAnti-S100B Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name S100B
Function Weakly binds calcium but binds zinc very tightly- distinct binding sites with different affinities exist for both ions on each monomer. Physiological concentrations of potassium ion antagonize the binding of both divalent cations, especially affecting high-affinity calcium-binding sites. Binds to and initiates the activation of STK38 by releasing autoinhibitory intramolecular interactions within the kinase. Interaction with AGER after myocardial infarction may play a role in myocyte apoptosis by activating ERK1/2 and p53/TP53 signaling. Could assist ATAD3A cytoplasmic processing, preventing aggregation and favoring mitochondrial localization. May mediate calcium-dependent regulation on many physiological processes by interacting with other proteins, such as TPR-containing proteins, and modulating their activity.
Cellular Location Cytoplasm. Nucleus
Tissue Location Although predominant among the water-soluble brain proteins, S100 is also found in a variety of other tissues
Research Areas
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$ 325.00
Cat# AF4282a
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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