|Application ||WB, E|
|Other Accession||NP_000097.3, NP_001020332.2, 1565|
|Calculated MW||55769 Da|
|Other Names||CYP2D6; cytochrome P450, family 2, subfamily D, polypeptide 6; CPD6; CYP2D; CYP2D7AP; CYP2D7BP; CYP2D7P2; CYP2D8P2; CYP2DL1; CYPIID6; P450-DB1; P450C2D; P450DB1; cytochrome P450 2D6; cytochrome P450, family 2, subfamily D, polypeptide 7 pseudogene 2; cyto|
|Target/Specificity||This antibody is expected to recognize both reported isoforms (NP_000097.3; NP_001020332.2).|
|Format||Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.|
|Immunogen||Peptide with sequence C-PTGQPRPSHH , from the C Terminus of the protein sequence according to NP_000097.3; NP_001020332.2.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||Goat Anti-CYP2D6 Antibody (C Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Responsible for the metabolism of many drugs and environmental chemicals that it oxidizes. It is involved in the metabolism of drugs such as antiarrhythmics, adrenoceptor antagonists, and tricyclic antidepressants.|
|Cellular Location||Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein|
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