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Goat Anti-ATF1 Antibody (N Terminus)

Purified Goat Polyclonal Antibody

     
  • WB - Goat Anti-ATF1 Antibody (N Terminus) AF4316a
    AF4316a (0.1 µg/ml) staining of A431 nuclear cell lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession P18846
Other Accession NP_005162.1, 466
Reactivity Human
Predicted Cow
Host Goat
Clonality Polyclonal
Calculated MW 29233 Da
Additional Information
Gene ID 466
Other Names ATF1; activating transcription factor 1; EWS-ATF1; FUS/ATF-1; TREB36; cAMP-dependent transcription factor ATF-1; cyclic AMP-dependent transcription factor ATF-1
Format Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
Immunogen Peptide with sequence EDSHKSTTSETAPQ-C, from the N Terminus of the protein sequence according to NP_005162.1.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGoat Anti-ATF1 Antibody (N Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ATF1
Function This protein binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Binds to the Tax-responsive element (TRE) of HTLV-I. Mediates PKA-induced stimulation of CRE-reporter genes. Represses the expression of FTH1 and other antioxidant detoxification genes. Triggers cell proliferation and transformation.
Cellular Location Nucleus.
Research Areas
Citations (0)

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References

Huang GL, Guo HQ, Yang F, Liu OF, Li BB, Liu XY, Lu Y, He ZW.

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$ 335.00
Cat# AF4316a
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