CD56 / NCAM1 / NKH1 (Neuronal Cell Marker) Antibody - With BSA and Azide
Mouse Monoclonal Antibody [Clone SPM489 ]
|Application ||IHC-P, IF|
|Other Accession||4684, 503878, P13592|
|Isotype||Mouse / IgG1, kappa|
|Calculated MW||180, 145 and 125kDa|
|Other Names||Neural cell adhesion molecule 1, N-CAM-1, NCAM-1, CD56, NCAM1, NCAM|
|Format||200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.|
|Storage||Store at 2 to 8°C.Antibody is stable for 24 months.|
|Precautions||CD56 / NCAM1 / NKH1 (Neuronal Cell Marker) Antibody - With BSA and Azide is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||This protein is a cell adhesion molecule involved in neuron-neuron adhesion, neurite fasciculation, outgrowth of neurites, etc.|
|Cellular Location||Isoform 1: Cell membrane; Single-pass type I membrane protein Isoform 3: Cell membrane; Lipid-anchor, GPI- anchor Isoform 5: Secreted.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
email@example.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
This MAb reacts with an extracellular domain (close to transmembrane) of CD56/NCAM. Three isoforms of neural cell adhesion molecule (NCAM) are produced by differential splicing of the RNA transcript from a single gene. The 135kDa isoform is the basic molecule, which is glycosylated or sialylated to produce the mature species. Anti-CD56 recognizes two proteins of the neural cell adhesion molecule, the basic molecule expressed on most neuroectodermally derived tissues and neoplasms (e.g. retinoblastoma, medulloblastomas, astrocytomas, neuroblastomas, and small cell carcinomas). It is also expressed on some mesodermally derived tumors (rhabdomyosarcoma). Anti-CD56 plays an important role in the diagnosis of nodal and nasal NK/T-cell lymphomas.
Gerardy-Schahn R; et. al. Int Journal of Cancer. Supplement, 1994, 8:38-42. | Michalides R; et. al. International Journal of Cancer. Supplement, 1994, 8:34-7. | K. Moolenaar et al.Cancer Research 50, 1102-1106, 1990 | Schol DJ; et. al. Int J Cancer. Supplement, 1988, 2:34-4
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at firstname.lastname@example.org.