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TSFM antibody - middle region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB |
|---|---|
| Primary Accession | P43897 |
| Other Accession | P43897, NP_005717, NM_005726 |
| Reactivity | Human, Mouse, Rat, Rabbit, Guinea Pig, Bovine |
| Predicted | Human, Mouse, Rabbit, Guinea Pig |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 38 kDa |
| Gene ID | 10102 |
|---|---|
| Alias Symbol | COXPD3, EF-TS, EF-Tsmt, EFTS, EFTSMT |
| Other Names | Elongation factor Ts, mitochondrial {ECO:0000255|HAMAP-Rule:MF_03135}, EF-Ts {ECO:0000255|HAMAP-Rule:MF_03135}, EF-TsMt {ECO:0000255|HAMAP-Rule:MF_03135}, TSFM {ECO:0000255|HAMAP-Rule:MF_03135} |
| Target/Specificity | The TSFM protein is a mitochondrial translation elongation factor. Synthesis of the 13 mitochondrial-encoded proteins occurs on a dedicated mitochondrial translation apparatus similar to that found in prokaryotes and requires, in addition to the tRNAs and rRNAs encoded in mtDNA, the concerted action of several translation factors and a large number of mitochondrial ribosomal proteins, all of which are encoded by nuclear genes.Synthesis of the 13 mitochondrial-encoded proteins occurs on a dedicated mitochondrial translation apparatus similar to that found in prokaryotes and requires, in addition to the tRNAs and rRNAs encoded in mtDNA, the concerted action of several translation factors and a large number of mitochondrial ribosomal proteins, all of which are encoded by nuclear genes. The TSFM gene encodes a mitochondrial translation elongation factor (Smeitink et al., 2006 [PubMed 17033963]).[supplied by OMIM]. |
| Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reconstitution & Storage | Add 50 ul of distilled water. Final anti-TSFM antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles. |
| Precautions | TSFM antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | TSFM {ECO:0000255|HAMAP-Rule:MF_03135} |
|---|---|
| Function | Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. |
| Cellular Location | Mitochondrion. |
| Tissue Location | Expressed in all tissues, with the highest levels of expression in skeletal muscle, liver and kidney |
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Provided below are standard protocols that you may find useful for product applications.
Background
This is a rabbit polyclonal antibody against TSFM. It was validated on Western Blot using a cell lysate as a positive control. Abgent strives to provide antibodies covering each member of a whole protein family of your interest. We also use our best efforts to provide you antibodies recognize various epitopes of a target protein. For availability of antibody needed for your experiment, please inquire (sales@abgent.com).
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