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>   home   >   Products   >   Primary Antibodies   >   Antibody Collections   >   Phospho Antibodies   >   CNOT7 antibody - middle region   

CNOT7 antibody - middle region

Rabbit Polyclonal Antibody

  • WB - CNOT7 antibody - middle region AI10068
    CNOT7 antibody - middle region (AI10068) in Human Placenta cells using Western Blot
    WB Suggested Anti-CNOT7 Antibody Titration: 0.2-1 μg/ml
    ELISA Titer: 1:62500
    Positive Control: Human Placenta
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9UIV1
Other Accession Q9UIV1, NP_037486, NM_013354
Reactivity Human, Mouse, Rat, Rabbit, Zebrafish, Pig, Goat, Dog, Guinea Pig, Horse, Bovine, Yeast
Predicted Human, Mouse, Rat, Zebrafish, Pig, Chicken, Goat, Dog, Bovine
Host Rabbit
Clonality Polyclonal
Calculated MW 33 kDa
Additional Information
Gene ID 29883
Alias Symbol CAF1, hCAF-1
Other Names CCR4-NOT transcription complex subunit 7, BTG1-binding factor 1, CCR4-associated factor 1, CAF-1, Caf1a, CNOT7, CAF1
Target/Specificity CNOT7 binds to an anti-proliferative protein, B-cell translocation protein 1, which negatively regulates cell proliferation. Binding of the two proteins, which is driven by phosphorylation of the anti-proliferative protein, causes signaling events in cell division that lead to changes in cell proliferation associated with cell-cell contact. The protein has both mouse and yeast orthologs.
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-CNOT7 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
PrecautionsCNOT7 antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CNOT7
Synonyms CAF1
Function Has 3'-5' poly(A) exoribonuclease activity for synthetic poly(A) RNA substrate. Its function seems to be partially redundant with that of CNOT8. Catalytic component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. During miRNA-mediated repression the complex seems also to act as translational repressor during translational initiation. Additional complex functions may be a consequence of its influence on mRNA expression. Associates with members of the BTG family such as TOB1 and BTG2 and is required for their anti- proliferative activity.
Cellular Location Nucleus. Cytoplasm, P-body. Note=NANOS2 promotes its localization to P-body.
Research Areas
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This is a rabbit polyclonal antibody against CNOT7. It was validated on Western Blot using a cell lysate as a positive control. Abgent strives to provide antibodies covering each member of a whole protein family of your interest. We also use our best efforts to provide you antibodies recognize various epitopes of a target protein. For availability of antibody needed for your experiment, please inquire (

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$ 293.00
Cat# AI10068
(40 western blots)
Availability: 2-3 days
Bulk Size
Seasonal Special on Bulk Order
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