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>   home   >   Products   >   Primary Antibodies   >   MLL4 antibody - N-terminal region   

MLL4 antibody - N-terminal region

Rabbit Polyclonal Antibody

  • WB - MLL4 antibody - N-terminal region AI10100
    MLL4 antibody - N-terminal region (AI10100) in Human HepG2 cells using Western Blot
    WB Suggested Anti-MLL4 Antibody Titration: 5μg/ml
    Positive Control: HepG2 cell lysate
    KMT2B is strongly supported by BioGPS gene expression data to be expressed in Human HepG2 cells
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9UMN6
Other Accession Q9UMN6-2
Reactivity Human, Mouse, Rat, Rabbit, Pig, Dog, Guinea Pig, Horse, Bovine, Yeast
Predicted Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Calculated MW 64 kDa
Additional Information
Gene ID 9757
Alias Symbol HRX2, MLL2, TRX2, WBP7, MLL4
Other Names Histone-lysine N-methyltransferase 2B, Lysine N-methyltransferase 2B, Myeloid/lymphoid or mixed-lineage leukemia protein 4, Trithorax homolog 2, WW domain-binding protein 7, WBP-7, KMT2B, HRX2, KIAA0304, MLL2, MLL4, TRX2, WBP7
Target/Specificity MLL4 a protein which contains multiple domains including a CXXC zinc finger, three PHD zinc fingers, two FY-rich domains, and a SET (suppressor of variegation, enhancer of zeste, and trithorax) domain. The SET domain is a conserved C-terminal domain that characterizes proteins of the MLL (mixed-lineage leukemia) family. MLL4 is ubiquitously expressed in adult tissues. It is also amplified in solid tumor cell lines, and may be involved in human cancer
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 100 ul of distilled water. Final anti-MLL4 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
PrecautionsMLL4 antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name KMT2B
Synonyms HRX2, KIAA0304, MLL2, MLL4, TRX2, WBP7
Function Histone methyltransferase. Methylates 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. Plays a central role in beta-globin locus transcription regulation by being recruited by NFE2. Plays an important role in controlling bulk H3K4me during oocyte growth and preimplantation development. Required during the transcriptionally active period of oocyte growth for the establishment and/or maintenance of bulk H3K4 trimethylation (H3K4me3), global transcriptional silencing that preceeds resumption of meiosis, oocyte survival and normal zygotic genome activation.
Cellular Location Nucleus.
Tissue Location Widely expressed. Highest levels in testis. Also found in brain, bone marrow, heart, muscle, kidney, placenta, spleen, thymus, prostate, ovary, intestine, colon, peripheral blood lymphocytes and pancreas. Often amplified in pancreatic carcinomas
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This is a rabbit polyclonal antibody against MLL4. It was validated on Western Blot using a cell lysate as a positive control. Abgent strives to provide antibodies covering each member of a whole protein family of your interest. We also use our best efforts to provide you antibodies recognize various epitopes of a target protein. For availability of antibody needed for your experiment, please inquire (

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$ 232.00
Cat# AI10100
(40 western blots)
Availability: 2-3 days
Bulk Size
Seasonal Special on Bulk Order
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