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PARP11 antibody - middle region

Rabbit Polyclonal Antibody

     
  • WB - PARP11 antibody - middle region AI10105
    PARP11 antibody - middle region (AI10105) in Human Muscle cells using Western Blot
    WB Suggested Anti-PARP11 Antibody Titration: 0.2-1 μg/ml
    ELISA Titer: 1:312500
    Positive Control: Human Muscle
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB
Primary Accession Q9NR21
Other Accession Q9NR21, NP_065100, NM_020367
Reactivity Human, Mouse, Rat, Rabbit, Pig, Dog, Guinea Pig, Horse, Bovine
Predicted Mouse, Rat, Rabbit, Pig, Chicken, Dog, Horse, Bovine
Host Rabbit
Clonality Polyclonal
Calculated MW 39 kDa
Additional Information
Gene ID 57097
Alias Symbol C12orf6, DKFZp779H0122
Other Names Poly [ADP-ribose] polymerase 11, PARP-11, ADP-ribosyltransferase diphtheria toxin-like 11, ARTD11, PARP11, C12orf6
Target/Specificity PARP1 encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes. PARP1 can be cleaved resulting in fragements of 29 and 85 kDa.
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-PARP11 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
PrecautionsPARP11 antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name PARP11
Synonyms C12orf6
Function Plays a role in nuclear envelope stability and nuclear remodeling during spermiogenesis (By similarity). In vitro, exhibits mono(ADP-ribosyl) transferase activity (PubMed:25673562).
Cellular Location Nucleus, nuclear pore complex. Note=Colocalizes with NUP153 at nuclear pores.
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Background

This is a rabbit polyclonal antibody against PARP11. It was validated on Western Blot using a cell lysate as a positive control. Abgent strives to provide antibodies covering each member of a whole protein family of your interest. We also use our best efforts to provide you antibodies recognize various epitopes of a target protein. For availability of antibody needed for your experiment, please inquire (sales@abgent.com).

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$ 293.00
Cat# AI10105
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