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>   home   >   Products   >   Primary Antibodies   >   Neuroscience   >   CRSP6 antibody - N-terminal region   

CRSP6 antibody - N-terminal region

Rabbit Polyclonal Antibody

  • IHC - CRSP6 antibody - N-terminal region AI10116
    CRSP6 antibody - N-terminal region (AI10116) in Human Brain cells using Immunohistochemistry
    Human Brain
  • CHIP - CRSP6 antibody - N-terminal region AI10116
    CRSP6 antibody - N-terminal region (AI10116) in HCT116 using CHIP
    Quiescent human colon carcinoma HCT116 cultures were treated with 10% FBS for three time points (0, 15, 30min) or (0, 30, 60min) were used in Matrix-ChIP and real-time PCR assays at EGR1 gene (Exon1) and 15kb upstream site.
  • IHC - CRSP6 antibody - N-terminal region AI10116
    Human Brain
    Rabbit Anti-MED17 Antibody
    Paraffin Embedded Tissue: Human neural cell
    Cellular Data: Epithelial cells of renal tubule
    Antibody Concentration: 4.0-8.0 μg/ml
    Magnification: 400X
  • WB - CRSP6 antibody - N-terminal region AI10116
    CRSP6 antibody - N-terminal region (AI10116) in Human HepG2 cells using Western Blot
    WB Suggested Anti-CRSP6 Antibody Titration: 0.2-1 μg/ml
    ELISA Titer: 1:12500
    Positive Control: HepG2 cell lysate
    MED17 is supported by BioGPS gene expression data to be expressed in HepG2
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9NVC6
Other Accession Q9NVC6, NP_004259, NM_004268
Reactivity Human, Mouse, Rat, Rabbit, Pig, Dog, Guinea Pig, Horse, Bovine
Predicted Human, Mouse, Rat, Chicken, Dog, Bovine
Host Rabbit
Clonality Polyclonal
Calculated MW 73 kDa
Additional Information
Gene ID 9440
Alias Symbol CRSP6, CRSP77, DRIP80, TRAP80
Other Names Mediator of RNA polymerase II transcription subunit 17, Activator-recruited cofactor 77 kDa component, ARC77, Cofactor required for Sp1 transcriptional activation subunit 6, CRSP complex subunit 6, Mediator complex subunit 17, Thyroid hormone receptor-associated protein complex 80 kDa component, Trap80, Transcriptional coactivator CRSP77, Vitamin D3 receptor-interacting protein complex 80 kDa component, DRIP80, MED17, ARC77, CRSP6, DRIP77, DRIP80, TRAP80
Target/Specificity The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by CRSP6 is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors.
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-CRSP6 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
PrecautionsCRSP6 antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name MED17
Synonyms ARC77, CRSP6, DRIP77, DRIP80, TRAP80
Function Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
Cellular Location Nucleus.
Tissue Location Ubiquitous..
Research Areas
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This is a rabbit polyclonal antibody against CRSP6. It was validated on Western Blot and immunohistochemistry by Abgent. At Abgent we manufacture rabbit polyclonal antibodies on a large scale (200-1000 products/month) of high throughput manner. Our antibodies are peptide based and protein family oriented. We usually provide antibodies covering each member of a whole protein family of your interest. We also use our best efforts to provide you antibodies recognize various epitopes of a target protein. For availability of antibody needed for your experiment, please inquire (

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$ 293.00
Cat# AI10116
(40 western blots)
Availability: 2-3 days
Bulk Size
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