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AFF2 antibody - N-terminal region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB |
|---|---|
| Primary Accession | P51816 |
| Other Accession | P51816, NP_002016, NM_002025 |
| Reactivity | Human, Mouse, Rat, Rabbit, Zebrafish, Pig, Dog, Guinea Pig, Horse, Bovine |
| Predicted | Human, Mouse, Rat, Rabbit, Pig, Guinea Pig, Horse, Bovine |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 145 kDa |
| Gene ID | 2334 |
|---|---|
| Alias Symbol | FMR2, FRAXE, MRX2, OX19, FMR2P |
| Other Names | AF4/FMR2 family member 2, Fragile X E mental retardation syndrome protein, Fragile X mental retardation 2 protein, FMR2P, Protein FMR-2, Protein Ox19, AFF2, FMR2, OX19 |
| Target/Specificity | AFF2 belongs to the AF4 family. Defects in AFF2 are the cause of FRAXE. The exact function of AFF2 remains unknown. |
| Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reconstitution & Storage | Add 50 ul of distilled water. Final anti-AFF2 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles. |
| Precautions | AFF2 antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | AFF2 (HGNC:3776) |
|---|---|
| Synonyms | FMR2, OX19 |
| Function | RNA-binding protein. Might be involved in alternative splicing regulation through an interaction with G-quartet RNA structure. |
| Cellular Location | Nucleus speckle. Note=When splicing is inhibited, accumulates in enlarged speckles |
| Tissue Location | Brain (most abundant in hippocampus and amygdala), placenta and lung |
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Provided below are standard protocols that you may find useful for product applications.
Background
This is a rabbit polyclonal antibody against AFF2. It was validated on Western Blot using a cell lysate as a positive control. Abgent strives to provide antibodies covering each member of a whole protein family of your interest. We also use our best efforts to provide you antibodies recognize various epitopes of a target protein. For availability of antibody needed for your experiment, please inquire (sales@abgent.com).
If you have used an Abcepta product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at tech@abcepta.com.
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