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FHL2 antibody - C-terminal region

Rabbit Polyclonal Antibody

     
  • IHC - FHL2 antibody - C-terminal region AI10132
    FHL2 antibody - C-terminal region (AI10132) in Human Heart cells using Immunohistochemistry
    Human Heart
    detail
  • WB - FHL2 antibody - C-terminal region AI10132
    FHL2 antibody - C-terminal region (AI10132) in Human heart cells using Western Blot
    WB Suggested Anti-FHL2 Antibody Titration: 0.6μg/ml
    ELISA Titer: 1:312500
    Positive Control: Human heart
    detail
  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC
Primary Accession Q14192
Other Accession Q14192, NP_963849, NM_201555
Reactivity Human, Mouse, Rat, Rabbit, Zebrafish, Dog, Guinea Pig, Horse, Bovine
Predicted Human, Mouse, Rat, Rabbit, Zebrafish, Chicken, Dog, Horse, Bovine
Host Rabbit
Clonality Polyclonal
Calculated MW 32 kDa
Additional Information
Gene ID 2274
Alias Symbol DRAL, AAG11, FHL-2, SLIM3, SLIM-3
Other Names Four and a half LIM domains protein 2, FHL-2, LIM domain protein DRAL, Skeletal muscle LIM-protein 3, SLIM-3, FHL2, DRAL, SLIM3
Target/Specificity FHL2 is a member of LIM proteins that contain a highly conserved double zinc finger motif called the LIM domain.
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 100 ul of distilled water. Final anti-FHL2 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
PrecautionsFHL2 antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name FHL2
Synonyms DRAL, SLIM3
Function May function as a molecular transmitter linking various signaling pathways to transcriptional regulation. Negatively regulates the transcriptional repressor E4F1 and may function in cell growth. Inhibits the transcriptional activity of FOXO1 and its apoptotic function by enhancing the interaction of FOXO1 with SIRT1 and FOXO1 deacetylation. Negatively regulates the calcineurin/NFAT signaling pathway in cardiomyocytes (PubMed:28717008).
Cellular Location Cytoplasm. Nucleus. Cytoplasm, myofibril, sarcomere, Z line {ECO:0000250|UniProtKB:O35115}
Tissue Location Expressed in skeletal muscle and heart.
Research Areas
Citations (0)
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Background

This is a rabbit polyclonal antibody against FHL2. It was validated on Western Blot and immunohistochemistry by Abgent. At Abgent we manufacture rabbit polyclonal antibodies on a large scale (200-1000 products/month) of high throughput manner. Our antibodies are peptide based and protein family oriented. We usually provide antibodies covering each member of a whole protein family of your interest. We also use our best efforts to provide you antibodies recognize various epitopes of a target protein. For availability of antibody needed for your experiment, please inquire (sales@abgent.com).

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$ 339.00
Cat# AI10132
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