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KLHL3 antibody - N-terminal region

Rabbit Polyclonal Antibody

  • IHC - KLHL3 antibody - N-terminal region AI10138
    KLHL3 antibody - N-terminal region (AI10138) in Human brain stem cells using Immunohistochemistry
    Sample Type : Human brain stem cells

    Primary Antibody Dilution : 1:500

    Secondary Antibody : Goat anti-rabbit Alexa-Fluor 594
    Secondary Antibody Dilution : 1:1000
    Color/Signal Descriptions : KLHL3: Red DAPI:Blue

    Gene Name : KLHL3
    Submitted by : Dr. Yuzhi Chen, University of Arkansas for Medical Science
  • WB - KLHL3 antibody - N-terminal region AI10138
    KLHL3 antibody - N-terminal region (AI10138) in Human THP-1 cells using Western Blot
    WB Suggested Anti-KLHL3 Antibody Titration: 0.2-1 μg/ml
    ELISA Titer: 1:12500
    Positive Control: THP-1 cell lysate
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9UH77
Other Accession Q9UH77, NP_059111, NM_017415
Reactivity Human, Mouse, Rat, Rabbit, Zebrafish, Pig, Dog, Guinea Pig, Horse, Bovine
Predicted Human, Mouse, Rat, Rabbit, Pig, Chicken, Dog, Guinea Pig, Horse, Bovine
Host Rabbit
Clonality Polyclonal
Calculated MW 65 kDa
Additional Information
Gene ID 26249
Alias Symbol FLJ40871, KIAA1129, MGC44594, PHA2D
Other Names Kelch-like protein 3, KLHL3, KIAA1129
Target/Specificity KLHL3 protein contains a poxvirus and zinc finger domain at the N-terminus and six tandem repeats (kelch repeats) at the C-terminus. At the amino acid level, KLHL3 shares 77% similarity with Drosophila kelch and 89% similarity with Mayven (KLHL2), another human kelch homolog. At least three isoforms are produced and may be the result of alternative promoter usage. The KLHL3 maps within the smallest commonly deleted segment in myeloid leukemias characterized by a deletion of 5q, however, no inactivating mutations of KLHL3 could be detected in malignant myeloid disorders with loss of 5q.
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-KLHL3 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
PrecautionsKLHL3 antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name KLHL3
Synonyms KIAA1129
Function Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex that acts as a regulator of ion transport in the distal nephron. The BCR(KLHL3) complex acts by mediating ubiquitination of WNK4, an inhibitor of potassium channel KCNJ1, leading to WNK4 degradation.
Cellular Location Cytoplasm, cytoskeleton. Cytoplasm, cytosol
Tissue Location Widely expressed.
Research Areas
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This is a rabbit polyclonal antibody against KLHL3. It was validated on Western Blot using a cell lysate as a positive control. Abgent strives to provide antibodies covering each member of a whole protein family of your interest. We also use our best efforts to provide you antibodies recognize various epitopes of a target protein. For availability of antibody needed for your experiment, please inquire (

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$ 293.00
Cat# AI10138
(40 western blots)
Availability: 2-3 days
Bulk Size
Seasonal Special on Bulk Order
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