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RBBP9 Antibody
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IF |
|---|---|
| Primary Accession | O75884 |
| Other Accession | O75884, NP_006597, NM_006606 |
| Reactivity | Human, Mouse, Rat, Rabbit, Zebrafish, Pig, Dog, Guinea Pig, Horse, Bovine |
| Predicted | Human, Mouse, Rat, Bovine |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 21 kDa |
| Gene ID | 10741 |
|---|---|
| Alias Symbol | BOG, MGC9236, RBBP10 |
| Other Names | Putative hydrolase RBBP9, 3---, B5T-overexpressed gene protein, Protein BOG, Retinoblastoma-binding protein 10, RBBP-10, Retinoblastoma-binding protein 9, RBBP-9, RBBP9, BOG, RBBP10 |
| Target/Specificity | RBBP9 may play a role in the transformation process due to its capacity to confer resistance to the growth-inhibitory effects of TGF-beta1 through interaction with retinoblastoma and the subsequent displacement of E2F-1.The protein encoded by this gene is a retinoblastoma binding protein that may play a role in the regulation of cell proliferation and differentiation. Two alternatively spliced transcript variants of this gene with identical predicted protein products have been reported, one of which is a nonsense-mediated decay candidate. |
| Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reconstitution & Storage | Add 50 ul of distilled water. Final anti-RBBP9 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles. |
| Precautions | RBBP9 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | RBBP9 |
|---|---|
| Synonyms | BOG, RBBP10 |
| Function | Serine hydrolase whose substrates have not been identified yet (PubMed:19329999, PubMed:20080647). May negatively regulate basal or autocrine TGF-beta signaling by suppressing SMAD2-SMAD3 phosphorylation (PubMed:20080647). May play a role in the transformation process due to its capacity to confer resistance to the growth-inhibitory effects of TGF-beta through interaction with RB1 and the subsequent displacement of E2F1 (PubMed:9697699). |
| Tissue Location | Expressed at higher levels in tumor tissues such as carcinoma. |
Research Areas
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$ 389.00
Cat# AI10143
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