|Other Accession||P54284, NP_000716, NM_000725|
|Reactivity||Human, Mouse, Rat, Rabbit, Pig, Dog, Guinea Pig, Horse, Bovine|
|Predicted||Human, Mouse, Rat, Pig, Dog, Horse|
|Calculated MW||53 kDa|
|Alias Symbol||CAB3, CACNLB3|
|Other Names||Voltage-dependent L-type calcium channel subunit beta-3, CAB3, Calcium channel voltage-dependent subunit beta 3, CACNB3, CACNLB3|
|Target/Specificity||The L-type calcium channel is composed of four subunits: alpha-1, alpha-2, beta and gamma. The beta subunit of voltage-dependent calcium channels contributes to the function of the calcium channel by increasing peak calcium current, shifting the voltage dependencies of activation and inactivation, modulating G protein inhibition and controlling the alpha-1 subunit membrane targeting.|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 100 ul of distilled water. Final anti-CACNB3 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||CACNB3 antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||The beta subunit of voltage-dependent calcium channels contributes to the function of the calcium channel by increasing peak calcium current, shifting the voltage dependencies of activation and inactivation, modulating G protein inhibition and controlling the alpha-1 subunit membrane targeting.|
|Tissue Location||Expressed mostly in brain, smooth muscle and ovary|
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This is a rabbit polyclonal antibody against CACNB3. It was validated on Western Blot using a cell lysate as a positive control. Abgent strives to provide antibodies covering each member of a whole protein family of your interest. We also use our best efforts to provide you antibodies recognize various epitopes of a target protein. For availability of antibody needed for your experiment, please inquire (firstname.lastname@example.org).
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